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Search Results for " clk1 in 1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T23897 CLK1/2-IN-3 CLK1/2 inhibitor 3,CLK1/2-inhibitor-3,CLK1/2 IN 3,CLK1/2IN3 CDK
CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, and SRPK3.CLK1/2-IN-3 induces nuclear speckle enlargement, wh...
T10836 CLK1-IN-1 CDK
CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).
T23896 CLK1/2-IN-1 CLK1/2 inhibitor 1,CLK1/2IN1,CLK1/2-inhibitor-1
CLK1/2-IN-1 is a CLK1 and CLK2 inhibitor and it also inhibits SRPK1 and SRPK2.
T61543 CLK1/4-IN-1
CLK1/4-IN-1 (compound 31) is a highly potent and selective inhibitor of Clk1 and Clk4, with IC50 values of 9.7 nM and 6.6 nM, respectively. It effectively inhibits the growth of T24 cancer cells, with a GI50 value of 1.1...
T74805 T74805
CLK1-IN-3 (compound 10ad) is a potent and selective Clk1 inhibitor, with an IC 50 of 5 nM and over 300-fold selectivity for Dyrk1A . CLK1-IN-3 also shows a relatively potent inhibition against Clk2 and Clk4 , with IC 50 ...
T73321 CLK1-IN-2
CLK1-IN-2, a metabolically stable Clk1 inhibitor, exhibits selective activity for Clk1 with an IC50 value of 1.7 nM. It is applicable in researching tumor, Duchenne's muscular dystrophy, and viral infections including HI...
T60394 Haspin-IN-2
Haspin-IN-2 (compound 4) is a potent, selective inhibitor of haspin, exhibiting an IC50 of 50 nM. Additionally, it inhibits CLK1 and DYRK1A, with IC50 values of 445 nM and 917 nM, respectively [1].
T60477 Haspin-IN-1
Haspin-IN-1 (compound 2a) is an inhibitor of haspin (haploid germ cell-specific nuclear protein kinase) with an IC50 of 119 nM. Haspin-IN-1 also inhibits CLK1, DYRK1A, and CDK9 with IC50 of 221 nM, 916.3 nM, and 406.8 nM...
T36684 Ipivivint
Ipivivint, a first-in-class, orally active and potent CDC-like kinase (CLK) inhibitor, inhibits CLK1 (IC50=1.4 μM), CLK2 (IC50=0.002 μM) and CLK3 (IC50=0.022 μM). Ipivivint reduces Wnt pathway signaling gene expression t...
TargetMol